Aside from the fact that both instruments have a tremolo bridge, humbuckers, and 24 frets, these are two very different instruments. Besides the obvious differences in body/headstock shape, body depth, the 'littlest dragon' inlay, and tone/vol pot locations, they are also a different scale-length. The Westy (24.5" scale) is a limited production instrument with a unique 'dragon' carve that is deeper than other Santana-shaped instruments. Westys have Brazilian Rosewood fretboards with hidden fret-tangs like the Santana 2 (a very cool feature). Westys have non-plated brass tremolo bridges which hearken back to the West Street days, this model's namesake. Finally, Sapele is in the Mahogany family and helps every Westy maintain that magic (in my opinion) combination of woods.
But it ain't all sunshine and lollipops. Assuming you are good with short-scale guitars and all that goes with them (like looser string tension and tonal differences), there is the possibility that your new Westy might be neck-heavy due to the delightfully thick neck carve and shorter upper horn. Each instrument is different and the one you buy might not have this issue but mine required some mitigation. After changing the metal tuning knobs for ebony and stacking two traditional PRS strap buttons on the upper-horn (with a longer screw), I'm good-to-go.
As a final thought, there are two versions of this guitar that I am aware of; the proper '1980 West Street Limited' with Dragon inlay and a much smaller run without the dragon inlay. I think the smaller run (seems like 10 or less made, Sergio prolly knows) also eschewed the BRW fretboard and hidden fret tangs. Be careful... there are sellers out there who love to call the later run '1980 West Street Limited' guitars. They are not. Is the smaller run cool? Yes. Is it limited? More so than the big dog. Is it worthy of the name Westy? Probably. But is it a true-blue 1980 West Street LTD? Not a chance.
Buy one while they're cheap. Try to find one with a 1-piece top. There are a few unicorns like Sergio's White Westy and Veinbuster's charcoal Westy. Most seem to be Vintage Orange or Vintage Cherry (my favorite).