Amplitube's models are excellent if you haven't got a tube amp, or need a sound that you haven't got in your hardware amp arsenal. IK did a good job with them. I've used them as scratch pads for coming up with parts that I later re-record with tube amps.
I'm not a fan of solid state hardware amps in general, and one of several reasons is that contrary to what we sometimes hear, they aren't good with overdrive pedals, A good overdrive (and I include the Boss line, lots of pros use them) is designed to drive a tube amp amp into clipping, whether a little or a lot. That way you get a blend of the pedal's distortion and the amp's distortion. It's a creamier sound, whereas pure solid state distortion is pretty harsh. But there's also the whole feel thing, and the fact that a solid state amp's built-in distortion is usually pretty awful, too.
So I'd rather use something like Amplitube with good sounding models, than the solid state amps. I can see why you like using that software..
Admittedly I'm kind of picky about tone, because my work winds up being broadcast. I compete with talented folks for the work, so anything that gives me an edge is good. But I have a little gear fund that I add to here and there for months to save for what I need.