Interesting topic Les. My (purely personal) take on this might be summarized as: "be careful what you wish for........"
I have nicely balanced pairs of both Two Rocks and Boogies: Custom Reverb Sig and LTD, and MkIIA and MkIIC+. My CRS has a clearer voice than the LTD, and the MkIIA has a similar relationship to the MkIIC+ in terms of "hearing all the way through".
I wouldn't say I prefer either end of these particular polarities, except in specific circumstances - in fact, I spend as much time using the two amps that define the mid-points between these pairs as I do at their extremes. That's to say, with my Two Rock Akoya and MkIIB Coliseum.
So no absolutes here
in terms of ultimate preference..... it's all down to the musical setting.
One thing's sure, however - when I want to hear as little "fur" as possible at rational volumes, and using any of these amps, then the Custom Reverb Sig paired with a low-wind single-coil pickup seems to get nearest to that ideal.
And yet...... and yet........ I'm aware, even at that point, of some amp "editorializing": all I have to do is plug in my Hiwatt DR103, with no pedals in the chain, and I have to work a lot harder to get "music" out of the combination of amp and guitar.
So maybe there are "absolutes" that really do get all the way down to the bone, the "truth" of what's coming off the hands/guitar. Do I generally want such alarming clarity?
Speaking as a decent journeyman player - one who can use a little extra "padding" - the answer's mostly no