If you plan on bending much, a plain 3rd is the way to go. I've used .010"-.046" sets for years, with the normal .017" G, but it does feel a bit stiffer than the others. I guess I'm just used to it after all these years! Albert Lee uses a .015" G--I may have to try that sometime, but I suspect I'd overbend it like crazy! I'm left-handed anyway, although I play right-handed, so my left hand is pretty strong. When I was a teenager in the mid-1960's, before I discovered light-gauge strings, I was trying (and failing) to bend a G string that must have been about a .026" wound, like you'd have on an acoustic, so I was building up strength and didn't know it. I'll never forget, thinking that if "Slinky" was good, "Extra Super Slinky" had to be even better--and I couldn't play those at all; I felt like I was playing on angel-hair pasta.
Tom--if you feel that you've got to have heavier strings for your 5th and 6th, you might try a light-top-heavy-bottom set--usually .010" on top to .052" or .054" on the bottom. I don't know if PRS offers that gauge, but D'Addario (who make PRS strings) do, and so do plenty of others. Make sure your neck will handle the unbalanced tension, though--some won't. Back in the early-'70's, I twisted the neck on my '67 Gibson ES-345 by repeated use of that set. I'd recommend that you try to get used to a regular .010"-.046" set if you can.