I'm going to take you into an alternate universe, one that combines the NF middle pickup with two Narrow 408 pickups. And I'm going to explain why one of these guitars might just be worth considering, assuming that you can find one.
For me, the NF pickup is the greatest middle pickup I've ever played. It's the perfect middle pickup, it does exactly what a middle pickup should do. However...as a bridge or neck pickup, played clean - and I stress that this might only apply to my own tastes - it tends to sound more humbucker than single-coil-articulate-sparkly-clear. Because it is, in fact, a humbucker. Yes, it's an articulate humbucker, but there are other options.
Enter the narrow 408. This pickup, even in full humbucker mode, sounds more like a single coil pickup. It's also more articulate than a split coil humbucker, including the split coils on my McCarty that are of course a recent PRS design.
What this amounts to is single coil clarity without single coil noise; an incredibly beautiful set of in-between tones; and a truly unique sound, especially considering what PRS is known for.
Of course, none of this matters for heavy distortion work, I'm speaking principally of clean sounds here, where I think the differences between the pickups is most pronounced, though I also love the guitar for overdriven sounds, I generally will go with a true humbucker as a preference.
The guitar in my alternate universe is the 20th Anniversary of PS Ltd. It's easily the most unique sounding, incredible guitar I've ever owned for times when I don't want a traditional humbucker sound.