I'm not crazy about these 85/15 pickups on my new Custom 24. I believe they are quality pups and probably sound just the way PRS intended. But, they are way too bright and brittle, and I can't seem to get any mid-range crunch in the bridge pup and little sustain on the neck pup. I just picked up an equalizer in an effort to boost some of the mid-range, but still struggling. My Mexican telecaster has more warmth and mid-range tone, played through the same amp, etc. (it just booms, screams and sings) I'll tinker with the 85/15's some more, but may end up looking for some humbuckers to drop-in. Kind of disappointing for the most expensive guitar I've ever purchased.
We're always searching for the tone in our head. Honestly, a CU24 is almost certainly never going to sound like a Tele neck. If you already have that sound covered with your Tele, then searching for a different tone from a different guitar is a good thing.
Now, the CU24 may just absolutely not produce the tone you want. PRS (and the Customs in particular) have their own tonality that is not like a Fender and not like Gibson. They are their own thing. You may not like the tone (and there's not a darn thing wrong with not liking the tone), but PRS builds their guitars (ESPECIALLY the Customs) to create their own voice.
I would say, first listen to your CU24 in terms of what it sounds like that is entirely different than the other guitars you have. Is there any part of this tonality you like? Can you EQ the tonality that accentuates its unique voice AND produces a tone you find pleasing? IF yes, then work with the pickups as they are.
If you can't get it to produce a tone you like AND you like how it plays and looks and feels then look into a pickup swap.
If it doesn't produce the tone you want and you aren't passionate about how the guitar plays, looks and feels then sell it and find something else. Guitars are tools AND they should encourage you to want to play and improve and explore. If the instrument doesn't do that for you then get a different instrument; no matter how expensive or pretty or popular it is.
However, I would really encourage you to not try to reproduce the tone of your Tele. The Tele already owns that tone, you have no need to reproduce it. Try to discover the voice of your new CU24 and determine if that voice provides something you like and want to pursue.
Tone searching is a never ending quest. One day you'll have it and the next you'll be searching for something totally different.