I've used Ernie Ball Super Slinky 10-46 my entire life it seems, decades to say the least. They sound great on my current strat also. I got my McCarty back in February which came with the PRS Signature 10-46's. They sounded great. Once I played the finish off of those, I went back with some D'Addario Chrome's in 11-50's. I hated the sound, they were mellow as I like. I just felt like they lost the string clarity, things got muddied up real fast.
So, I pulled them off after about two days. And I put my Ernie Balls on, since I buy them in bulk. I didn't like those on the McCarty though. My strat is single coil and honestly. I've never owned a guitar with humbuckers, but it seems to change the string dynamics. They were responsive, but after the PRS Sigs, and the D'Addario's. The Ernie Balls were too flimsy. LOL. I went back with the PRS Sigs, and they are just wonderful again.
Any of you guys still play on the PRS strings?