This comparison was performed within one hour between the 3 guitars going through a Fender Tube amp with clean channel. The Silver Sky strings were not new but also not very worn either. The other guitars had new strings on them. I will be going back to spend more time with the Silver Sky. The Fender Professional sounded much different than the other two. It had less mid range, was not as thick and had a very clear bell tone. Great quack, and the 9.5 radius seemed a little more comfortable for me as a person who is 6' tall. It seems to have a slimmer sound with a nice chime. The neck does not have a lacquer so its easy to move up and down the neck. The 1st position has a little less top end shrill than the 1982 Strat...thankfully. It appeared to be constructed well and I didn't see any defects on it. My 1982 Strat had the 7.25 radius neck, and had a thicker tone than the Professional. The 1 position has way too much top end, and I usually have to back off the treble on my amp. It quacks very nice and it has great tones. The back of the neck has a lacquer and though I can move back and forth on the neck, a non lacquer neck is a little easier. The Silver Sky neck does not feel like a Strat neck. It has its own personality, just as Carvin/Kiesel, and Ibanez Strat type of guitars has. The neck is a joy to play on and the tuning pegs are easy to use to get slight changes of the string from flat to sharp and in between. The saddle quality gives an appearance of better quality than my 82 Strat. The pole on the high E string is lower than the other poles. This may attribute to it having a little less top zing. I found the overall sound closer to my 82 Strat than the Professional. It quaked a little less than either Stratocaster and it did not feel like a want to be Strat but its own personality though very similar. When playing the guitar and you feel and see the different neck and headstock, you get a different feeling playing it compared to the Fenders. You don't think I'm playing a copy Strat but a guitar with its own personality. However I saw two YouTube videos that compared the Fender John Mayer Strat to the PRS Silver Sky and they sounded so close in both videos. It would really just be a personal preference on which you want. One thing I notice was the back of the guitar did not have a block but a rounded connection from the neck to the body. This gives a more modern look and the access to the higher notes above 19 perhaps a tad easier. Toggle switch 1 had a more controlled top end and less shrill than either other Strat. All positions sound great. The neck size of course is like my 1982 Strat. I would say it has a 10 percent sound difference compared to my Strat. I will have to spend more time with it to get a better idea of its differences. It appeared to have a little less mid and the tone has a little more even sound compared to my Strat.