Cool, Yankee. Sounds like a pretty complex rig.
I run everything old-school, into the front of the amp. I've had a lot of amps with effects loops, but for some reason I like what happens with my pedals in front.
I run the HXDA into a Mesa 2x12 Recto cab, standard V-30s. I mainly run guitar into a Fulltone Clyde Deluxe >> Fulltone '69 >> Eventide ModFactor >> HXDA.
I was using a TC Nova Delay that sounded great, but with the gain cranked running into the front of the amp the unit's hiss was exaggerated, so I'm ordering an Eventide TimeFactor that is a little quieter. It also does a few more things. I am also in the process of replacing a Fulltone Mini Deja Vibe with the new one with the rocker pedal. Seems like I'm never done screwing around with this pedal stuff!