You've probably already seen my rants on the HDRX 20, so I'll save you the stuff I've already said in other threads.
Speaking of PRS amps in general, I find them to be very unfiltered, raw, and open - in the best way! Some amps I've played felt like they were doing some strong tone shaping, almost to feel or sound like the "album version" of the sound, not the amp it came from. PRS amps will give you everything the circuit has available, they have a flavor depending on the model, but in general they're also not cutting things out of the signal to great extent. It can make for an adjustment period, but once you do, amps that behave in the more overly groomed fashion feel way less open and almost choked down. The PRS amps also let a lot of the character of the guitar through, instead of trying to persuade everything to sound the same.
If you think you'll enjoy the features and tone of the HDRX 20, I'd definitely say go for it. It'd be hard to find a classic guitar tone loving person who didn't like it.