These are all great points! I've done the same to my 245 as Alnus. I've also upgraded to the PRS composite nut on all of my PRS SE, and brass nuts on a couple too
The major difference in feel will be the neck carve...Wide Fat for the Santana and 245 and Wide Thin for the SE CU24. You should try playing before buying one. They feel diff, and personally I didn't like the Wide Thin feel. I'm up to 7 PRSi since I joined here (ya darn enablers) and they are all Wide Fat necks.
Hope this helps and good luck. I may throw A 2017 SE Santana on Reverb soon and will PM you if I do. It will be a good price.
Thanks for the input. Yes, do PM me if you end up listing on Reverb. Thanks.