I find a wide variety of necks fall immediately into my range of acceptability. I can immediately feel the difference, but if I like it, I have no problem adapting immediately. My JP12 has a THIN neck a very flat fretboard. But I have no problem flipping from it, to my Wolfgang, which is a wide C, Eddie neck. But I have never liked Wizard necks even though I loved Ibanez guitars when the Wiz came out and have other Ibanez guitars that just rock. One of my friends has an Ibanez with a Wizard neck and I hate the whole feel of it. As soon as I picked it up the first time I just said "no, not for me!" And I tried every time I saw him and could never like that guitar. But my JS100 is great. And my 79 Artist is my first real guitar and a GREAT overall guitar.
I have 4 PRS core guitars with 4 different neck profiles and I love them all and have no problem flipping between them. I tried a Bernie on vaca last year and the few minutes I played it, it, I didn't love it. Might be "adaptable" but it wasn't an immediate "love it" like the cores. I love some strat necks, but don't like the string feel. I don't like some LP necks but love the tones.... when you have to play the thing, you have to like what you FEEL. That's why PRS is #1 for me. I put one in my hands, and it just "Feels right!"