I think this is a big part of the discussion. I mainly care about live sound, so the Kemper and Headrush meet my needs well without weight issues and multiple pedals. The other factor is the genre of music. I play mostly classic and hard rock. If I were concerned with cleaner tones, I’d probably gravitate more towards tube amps.
I’ve been fortunate enough to attend several sound checks and gigs with Lonestar lately. The live tones Kemper guru, Michael Britt, gets are just killer!
I think the Kemper and other modelers are great for live work, for a number of reasons. I'd just go direct, modeler into mixer. The weight savings alone would be worth the small sacrifice in tone.
But yeah, the genre of music is also an important consideration!
I suppose I could get by with something like my Fillmore head and a load box with IRs as well; the Fillmore 50 is only 26 pounds, which isn't too bad. But there's still the issue of the pedalboard, and whether the sound person has decent mics and knows how to mic an amp, and on and on.
What you're using seems like a very smart choice.
For my recording purposes, different story - provided I either have the right amp on hand, or can rent or borrow one if the music is a different style from my 'usual'. But then, I'm miking up a cab with multiple mics most of the time. And that lends an 'in the room' vibe that's hard to model, though I once tried running a modeled track a session player sent me through my studio monitors, and miking my monitors to get a room sound.
I would like to say it worked, but...the modeler sounded better by itself.