I have almost religious approach to setup, but... not on daily basis. I usually take my time with full setup once in 4 months or so. That includes trust rod adjustment if necessary, string radius on the bridge side, and intonation.
Since I play 11-50 string set I opt for as low setup as I can get away with. I'm not a soft player so neck needs a bit of relief but my setup is still lower than of most of my jam mates