I have a 2006 CU22 ... it sounds great direct to the amp ... I only have a Fender DRRI and Super Champ XD ... my pedal board is very minimal and I am predominantly a clean tone player ... just as the first responder, I have found I enjoy playing more with less "clutter" b/t guitar and amp ... less to fiddle with and more concentration on enjoying the tones from the guitar ... PRS pickups have the quality to produce pleasing tone w/o much "interferance" or enhancement ... these days, I find myself using just a little delay and/or reverb and that's about it ... I don't think the DRRI is the best choice of amps for PRS guitars, but it works for me ... the Super Champ has a little less "bite" and brightness but also less "umph" and volume ... but at low volumes, it is very satisfying to me ...