Gonna hazard to say that intonating a guitar is much like maintaining your car. You listen to the engine for unusual noises, add fluids, check the brakes, and of course, check the horn. There are other things, but this will suffice. Correct neck bow will prevent fret buzz and/or too-high action. Saddle adjustment will bring the string length correctly proportionate for 12-fret harmonics, and lastly, the pickup height tweak will be like increasing or decreasing the volume/tone of your horn. No one wants a little bicycle horn, or worse, foghorn, so correct adjustment is needed. Off to the "garage" for a bit. Will report back once some .008s have made their way onto my McCarty.