I put GOTOH vintage Maglock locking tuners on my Zach Myers SE electric . They have the same mounting screw pattern as the original vintage style tuners but the peg holes had to be enlarged to use the new Gotoh bushings. They lock with a wheel on the backside. They really improved tuning stability on that model. Lots of slop in the OEM's. I shuddered at the prospect of using a drill on that beautifully veneered headstock. Don't try it. Get a peg head reamer from Stew Mac or take it to your local luthier.I will be putting lockers on my Angelus later this month, but I typically use Gotoh Mag Locks. Often they are less expensive than SE locking tuners and I like the big thumbwheel locking posts.
Honestly, I see no downside save for the installation time and extra cost, but they are such timesavers on string changes. The Gotoh models have some nice keys on them too.