I have Adirondack Spruce on my PS acoustic, with maple back, sides and neck, ebony fretboard, and carbon fiber truss rod.
It sounds as big and powerful as a grand piano - bold, responsive, yet capable of nuance as well. The idea behind the PRS acoustics is that you want the top to vibrate to project the sound, more so than the back and sides, so it's stiffly braced in the body, while the top vibrates more freely..
Nothing gives you that like Adirondack Spruce.
This isn't to say other tonewoods can't sound good, but they'll be different. Even European or Sitka spruce are a bit different from Adirondack and from each other.
The reason spruce is the traditional choice for stringed instruments like the guitar and violin families is that it's a flexible material, yet it's strong. As you get more into hardwoods, the flexibility that's needed for projection of the tone is impacted. A similar comparison can be made between condenser mics, with their very light mylar diaphragms, and dynamic mics, with their heavier paper cone diaphragms. Condensers will give you more immediacy and sparkle, dynamics will give you something else.
Cedar is more subdued, very well suited to classical guitars, and mahogany is different, too.
If looks are what's most important in your build, or you just feel like something different from a traditional acoustic guitar sound, I won't feel badly if you decide to completely ignore my post!